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Projects on "6.7 Development and validation of alternative methods to animal testing"
Estimating the risk of substances by spatial multi-biomarker profiling of 3D tissue cultures
Project code:
BfR-ZEBET-08-1328-192
Excutive institution:
BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period:
2006
- 2009
Evaluation of optimal transport condition for the shipping of human organotypic corneal equivalents for in vitro drug absorption studies
Project code:
BfR-ZEBET-08-1328-488
Excutive institution:
BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period:
2011
- 2014
Gastric cell lines to substitute native cells of the gastric gland to study acid secretion in special consideration of preclinical studies
Project code:
BfR-ZEBET-08-1328-190
Excutive institution:
BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period:
2005
- 2008
Generation of three dimensional vascular tissues and establishment of long-term cultures for establishing a multi-organ chip as an alternative to repeated dose (systemic) toxicity testing in vivo
Project code:
BfR-ZEBET-08-1322-601
Excutive institution:
BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period:
2014
- 2014
High-throughput methods for the estimation of toxicological effects of nanomaterials
Project code:
BfR-ZEBET-08-1329-475
Excutive institution:
BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period:
2011
- 2015
HPCT-1E3 hepatocytoma cultures for determination of cytotoxicity, toxicokinetic interactions and cholestatic effects, pre-validation study
Project code:
BfR-ZEBET-08-1328-174
Excutive institution:
BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period:
2004
- 2008
Human organotypic corneal equivalents for in-vitro drug absorption and metabolism studies
Project code:
BfR-ZEBET-08-1328-306
Excutive institution:
BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period:
2009
- 2014
Identification of electrophysiological endpoints in stem cell-based models for developmental neurotoxicity assays
Project code:
BfR-ZEBET-08-1328-491
Excutive institution:
BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period:
2012
- 2013
Improvement of the embryonic stem cell test (EST) using neural marker genes for testing the developmental neurotoxicity in vitro
Project code:
BfR-ZEBET-08-1322-295
Excutive institution:
BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period:
2004
- 2010
Improving the gain of transgenic mouse embryos for cryopreservation
Project code:
BfR-ZEBET-08-1328-191
Excutive institution:
BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period:
2005
- 2006
