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Projects on "6.7 Development and validation of alternative methods to animal testing"

In vitro exposure of lung cells with aerosol at the air-liquid-layer as an alternative for inhalation experiments with animals

Project code: BfR-ZEBET-08-1328-182
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2004 - 2007

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Joint Project: Development of an in vitro embryo toxicity tests with mouse embryonic stem cells: Subproject 1 - Analysis of embryotoxic effects in the light of new endpoints and metabolism using an expanded selection of materials

Project code: BfR-ZEBET-08-1334-168
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2004 - 2007

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Joint project: Pluripotent stem cells in automated prediction of developmental osteotoxizität. Subproject 3: Development and establishment of a Osteoblsten differentiation assays

Project code: BfR-ZEBET-08-1334-183
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2009 - 2010

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Mechanisms of Critical Illness-induced Cognitive Dysfunction

Project code: BfR-ZEBET-08-1336-105, A-2014-223
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2016 - 2018

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Mechanistic investigation of the influence of potential ED in the model organism C. elegans

Project code: BfR-TOX-08-1322-732
Excutive institution: BfR - Department 9: Experimental Toxicology and ZEBET
Contract period: 2018 - 2019

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Normal human neural progenitorcells as a screening model for substances that are toxic for neural development

Project code: BfR-ZEBET-08-1328-178
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2004 - 2007

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Optical probe technique for the assessment of multidrug resistance profiles in 3-dimensional in vitro tumor models

Project code: BfR-ZEBET-02-1328-181
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2004 - 2006

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Optimizing the pain management in the mouse-osteotomy-model – Integration of a refinement study in a basic research study (RefineMOMo)

Project code: BfR-ZEBET-08-1328-542
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2016 - 2016

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Organotypic cell culture models of human nasal mucosa for in-vitro drug absorption studies

Project code: BfR-ZEBET-08-1328-469
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2011 - 2013

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Predictive cardiotoxicity testing based on human stem cell-derived cardiomyocytes

Project code: BfR-ZEBET-08-1328-539
Excutive institution: BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
Contract period: 2015 - 2017

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