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Coordinated projects of "BfR - Centre for Documentation and Evaluation of Alternatives to Animal Experiments"

Replacement of fetal calf serum in the embryonic stem cell test (EST) – Standardization of culture conditions for proliferation and differentiation of embryonic stem cells of the mouse

Project code: BfR-ZEBET-02-1322-159
Contract period: 2004 - 2007
Funding institution: Federal Ministry of Food and Agriculture (BMEL) , Federal Institute for Risk Assessment (BfR)

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The isolated perfused bovine udder as an in vitro model for the evaluation of sensibilisation/sensitisation induced by chemicals

Project code: BfR-ZEBET-02-1328-175
Contract period: 2004 - 2006
Funding institution: Federal Ministry of Food and Agriculture (BMEL) , Federal Institute for Risk Assessment (BfR)

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HPCT-1E3 hepatocytoma cultures for determination of cytotoxicity, toxicokinetic interactions and cholestatic effects, pre-validation study

Project code: BfR-ZEBET-08-1328-174
Contract period: 2004 - 2008
Funding institution: Federal Institute for Risk Assessment (BfR)

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Evaluation of Alternative Methods to Animal Experiments in Life Sciences

Project code: BfR-ZEBET-02-1328-195
Contract period: 2004 - 2007
Funding institution: Federal Ministry of Food and Agriculture (BMEL)

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Normal human neural progenitorcells as a screening model for substances that are toxic for neural development

Project code: BfR-ZEBET-08-1328-178
Contract period: 2004 - 2007
Funding institution: Federal Institute for Risk Assessment (BfR)

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Development and Validation of an Inductive Database for the Prediction of Carcinogenic Effects of Chemicals

Project code: BfR-ZEBET-02-1328-179
Contract period: 2004 - 2005
Funding institution: Federal Institute for Risk Assessment (BfR)

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Characterisation and prevalidation of a new human cornea equivalent model for the evaluation of ocular toxicity

Project code: BfR-ZEBET-02-1328-180
Contract period: 2004 - 2006
Funding institution: Federal Institute for Risk Assessment (BfR)

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Optical probe technique for the assessment of multidrug resistance profiles in 3-dimensional in vitro tumor models

Project code: BfR-ZEBET-02-1328-181
Contract period: 2004 - 2006
Funding institution: Federal Ministry of Food and Agriculture (BMEL) , Federal Institute for Risk Assessment (BfR)

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Prevalidation of human cornea model based on immortalized corneal cell lines as in vitro alternative to the Draize eye test.

Project code: BfR-ZEBET-02-1328-184
Contract period: 2004 - 2006
Funding institution: Federal Institute for Risk Assessment (BfR)

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List of chemicals with missing IC 50-values and/or LD 50-values

Project code: BfR-ZEBET-02-BfR-Quer-02-A-1328
Contract period: 2004 - 2004
Funding institution: Federal Institute for Risk Assessment (BfR)

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